目录

Local Effect of MEBO on Wounds of Different KindS of Burns

（Abstract)

(Burn Centre, No.91 Hospital of PLA)

We treated 123 cases of burn using MEBO from September 1989 to May 1991. Most of the patients had moderate and small area burns. with an average burn area of 11.3%BSA (ranging from 0.5 to 52%BSA). Among which 30.08% had 3rd degree burns. This paper reports the clinical experience in treating deep 2nd degree and 3rd degree burns. Bacteria count on the wounds surface treated with MEBO was found to be XG(geometrical mean) = 5.72 x 104/cm2. Bacteria count in the inner layer of the Wounds was XG = 1.68 x 104 /cm2. (U= 4.01, P<0.01 ). Bacteria count on the wound surface treated with SD--Ag and SD--Zn was found to be XG =0.83 x 104/cm2. The difference between the MEBO treated and SD--Ag or SD--Zn treated groups was not significant. But wound surface bacteria culture of the patients treated with SD--Ag and SD--Zn had 73.9% detective rate for Pseudomonas aeruginosa. while MEBO treated Patients had a detective rate of 34.5% (X2=8.406, P<0.01 ). This.result showed that MEBO is more effective for inhibiting the growth of Pseudomonas aeruginosa. Wounds surface treated with MEBO had lower PH value than treated with SD--Ag or SD--Zn. Wounds treated with MEBO healed more quickly. The authors concluded that MEBO is better than conventional dry exposed therapy and has a promising prospect.

An Investigation of the Morbids of 2485 Cases of Bums in the Middle South Region of Hebei Prohoce and Suggestions of Prevention Measures

(Aboact)

Qi Shareken, et al.

(Dept. of Burn, hornationai Peace Hospitai Named After Dr. Normau Bethune)

2485 cases of burn in the Middle South Region of Hebei Province had been admitted to the hospital in the period from May. 1958 to December, 1989. Statistics for morbidity revealeds Male; female= 3.91. The highest morbidity was aming children at the age below 5, accounted for 30.91% of the total. The next was among the young people aging from 21 to 25, accounted for 20.85% The highest incidence was found in June, July and August. accounted for 33.16% of the whole year. Scalding liguid and flame were the main causes of burns. accounted for 44.39% and 41.89% respectively. Third degree burns were mostly caused by electricity, molten iron and steel and hot metals. Burn in the cephalocervical part had the highest incidence accounted for 43.82% of the total. Burn in upper limbs accounted for 40.8% Most of the burns had an area less than 5% TBSA. accounted for 34.69% 6 to 10% TBSA burns accounted for 22.89% Burns with an area exceeding 11% had low incidence. the larger the area, the lower the incidence. As for occupational distribution. the greatest risk was in the preschool children. accounted for 31 .75% among which more than 80% were in the rural areas and more than 95 % of the burned belonged to families having manV children. The next greatest risk of burn was in peasants and workers. accounted for 29.46% and 17.54% respectively.

On the basis of the data mentioned above, the authors suggested that for prevention of burn.it is necessary, 1. to heighten people'5 consciousness of fire prevention. The authors appealed the departments concerned to carry out active propaganda to improve the knowtedge of burn prevention among the masses. 2. To prevent burns in children. it is important to adhere to the policy of one chitld for a married couple, so that the parents can give the child the best of care. 3, The key to the prevention of chemical burns is to strengthen the safety education and to keep the production and the use of chemicals in line with regulations and rules and to raise the technica level of the workers.

An investigation of the Morbidity of Burns in Shaoxing Prefecture in the Past Five Years

(Aheact)

Jin Xingwei, et al.

（Burn Center , The 2nd Hospital of Shanoxing Prefecture , Zhejiang Province)

Our hospitaf is a prefecture level burn centre. We carried out a social investigation among the . inpatients and outpatients in the past five years, for the purpose of making a plan for taking measures of prevention and setting up network of treatment.

From January 1985 to December 1989, we received 7746 outpatients. and 1250 inpatients. Maled female= 2.44:1,healing rate : 99.1% death rated 0.9% In the past five years, the total number of outpatients of first visit was 23238 in the prefecture region and the total number of inpatients was 251 6 and the average annuaf number of outpatients and inpatients was 4647.6 and 503.2 respectively. In our prefecture. we have a population of 4. 103. 000. Annual burn morbidity was 0.113% Hospitalization rate: 0.012% The highest incidence in a year was in the months from May to September. accounted for 5381% of the total outpatients. Aged Adults 66.76% Children 29.67% and the old 3.57% Occupation : Workers 71 .6% Peasants 19.21 % Students 4.94% Cadre 2.1 9% and others 2.06% Industrial accident 43.5% including operating against the rules and regulations or using obsolete and unrepaired equipment. Burns other than industrial accident 55.59 % inctuding overturn of a thermosbottle and spilling of hot liquid. etc. Artificially imposed burn 0.91% Burn area : 0.5 to 94% TBSA, 3rd degree burn area O to 87% Average burn area 9.50 15.37 % Average 3rd degree burn area 1.40 5.26% Causes f Hot liquid 43.32 % Flame 25.46% Steam 10.35% Hot pressing 2.2 % Other thermal injuries 5.49% Explosion 1 .83% Chemical burns 7.05% Electric shock 2.11% and Electric arc 2.20%

Studies on Blood Coagulation Function at the Early Stage of Burns. IV Moaitoring and Diagnosis of Disseminated intravascular Coagulation

(Abstract)

Zhang Xiangqing, at al.

(No.91 Hospital)

Disseminated intravascu far coagu lation (DIC) is a major complication. of various severe diseases. The characteristic clinical manifestation is hemo-- rrhage. Many patients can be diagnosed only after hemorrhage has occurred. The authors proved that burned patients and scalded animals. before significant hemorrhage occurred, had marked abnormality in their coagulation and fibrinolytic systems. These abnormal changes determined the occurrence and the development of DIC. Consumptive coagulopathy (thrombopenia, prolonged proth-- rombin time, etc.) was the main cause of DIC. Marked lowering of plasma fibrinogen level had not been observed. This was relevant to the stress state at the early stage of burn. Hypocoagulability was a manifestation at the late stage of DIC. Large amount of blood coagulation factors had been consumed and exhausted, so that the in vitro thrombus weight was redu.ced markedly before the an imals d led.

Laboratory criteria of the diagnosis of DIC:Progressive reduction in the count of blood platelets (average value: 61.62 : 27.39 x 109 / L) is the main criterion of diagnosis, There is a temporary enhancement of platelet adhesion and aggregation functions at the early stage, but at the late stage. the functions turn to decline. Other changes in blood coagulation and fibrinolytic systems include prolonged prothrombin time and prothrombin time, increased positive rate of protamine paracoagulation test and ethanol gel test. Euglobulin lysis test is not as sensitive as the above mentioned criteria for monitoring and diagnosis of D I C, at the early stage of burn.

Present Statos of the Research of Post--burn Cell ImmunoSuppression Mechanism Suppression Mechanism

(Abstract)

Xie Youfu, et al.

(Hunan Medical Universit)

The mechanism of post--burn cell immunosuppression is now an active topic of research. It is a problem not yet wed clarified. The following may be important factors:

1. Activation of T suppression cell and / or inhibition of T helper lymphocyte. 2. The presence of immuno--suppression factors in the plasma post--burn. such as burn toxin, metabolite. etc. 3. Disorder and unbalance of the function and the metabolism of imterteukin 1 and 2 and other bioactive factors. 4. Intervention of oxygen free radical in the process of post--burn cell immuno-suppression.

In recent years. the research has been focused on the changes in immuno--reaction factors and the interrelation betWeen these factors. for the purpose of finding out the initiating factors of post--burn immuno--reactions and the course of their development. The authors Suggested that oxygen free radical and lipid peroxidation may possibly be the initiating factors of post--burn immuno--reactions and are worthy to be further investigated.

225 Cases of Burn Healed by Moist Exposed Therapy

(Abstract)

Dept. of Burns, The 2nd Hospital for Staff and Workers, Yanzhou Mining Bureau

225 cases of various kinds of burn had been treated in our hospital from May 1989 to March 1991. The largest burn area was 76% BSA. The average burn area was 10.36% BSA. 16% had deep 2nd degree burns and 35% 3rd degree burns. 67 cases of 3rd degree burn had an average area of 3rd degree burn of 7.1 5% All the patients were treated with moist exposed therapy invented by Prof. Xu Rongxiang. 96.89% of the patients healed. Clinical practice proved that the therapy has good analgesic and ' antiinfective effects. No scar formation for 2nd degree burns and only very soft or piebald scar for 3rd degree burns. The inspection of the wound surface is very convenient. For deep burns. if the drug is used in combination with lancet, the therapeutic course can be shortened and the healing process promoted. The authors used a technique called a electric heat mattress small space thermostatic method" to keep the external environment of the wound at a constant temperature. This method is safe. convenient and economical. The key to the reduction of death rate and the incidence of shock and other complications is to treat the patient timely without delay.

Clinical Report of 191 cases of Burn and scald Treat6d with Moist Exposed Therapy

(Abstract)

Qiao Haibin

(Clinic of the institute for welfare of ctheren, Nehe)

This paper reports the clinical experience in treating 191 cases of burn and scald from Nov. 1989 to June 1990, using moist exposed therapy and MEBO. The results were very satisfactory. The largest burn area was 32%BSA and the smallest 2% 131 cases had Superficial 2nd degree burn, 56 cases had deep 2nd degree burn and 4 cases had superficial 3rd degree burn. 2 typical cases were described in detail. The author concluded that moist exposed therapy had the followics characteristics: 1. Antiinfective effect. 2. Analgesic effect. 3. Epithelium regeneration promoting effect. 4. Scar formation lessening effect. 5. Liquefaction and drainage promoting effect. The author made a discussion on the efficacy of the therapy.

A Case of Melt6d Rosin Burn Healed by MEBO

(Abstract)

Hu Keyi, et al.

(Dept. of Surgery, Oil Field Construction Hospital, Nanyaug on Field, Henau Province)

This paper reports the application of MEBO in the treatment of the burn caused by melted rosin. The patient with burn area amounted to 10%TBSA was healed in 15 days. Burn caused by melted rosin is not common in clinic. Reports dealing with melted rosin burn are rare. The application of MEBO enriched the clinical experience in the treatment of burn caused by melted rosin.

Experience with MEBT in Treating Chemical Bums

(Abstract)

Yu Xien

(Hospital of Cheforal Industrial Corportstiou, Nabbing)

253 cases of burn among them 43 cases had chemical burns were.treated in the hospital. from June 1989 to May 1991. using MEBO. All of the 43 cases of chemical burn were healed. The reSults were satisfatory. Most of the burns were caused by sulfuric acid. nitric acid, pitch. liquid ammonia. etc. involving head. face and neck. Chemical burns in eye and ear were also seen. The largest burn area was 50%TBSA. Deep and Superficial 2nd degree burn accounted for 67.4% 3rd degree burn accou "ted for 4% The author suggested that it is important to make thorough debriedement as early as possible. The wounds should be washed with sterile water and normal saline for at least 30 minute. For alkali. phosporus, chromic acid and hydrofluoric acid burns, the washing should be continued for more than an hour. to ensure complete removal of the chemicals. Eye burns should be washed prior to burn of the other part of the body. Different kinds of burn should be treated in different ways. After debriedement. MEBO is applied. Dressing change is carried out at different time intervals, in accordance with the depth of the wounds.

The author concluded :that MEBO has wide application in treating burns. It has good analgesic and "neutralizing- effects and promotes the heating of the wounds. The following are the main points for attention : 1. First aid before hospitalization and early debriedement. 2. proper application of MEBO. 3. Systemic treatment.

Experience with Moist Exposed Therapy in Treating Panfacial Deep Burn

(Abstract)

Wu Xiwnin, ac al.

(Dept. of Burn, The 18t People's Hospital, Lianvunoano City. Jiangsu Province)

Deep burns involving whole face is a severe case difficult to manage because of the anatomical, pathological and physiological characteristics o f the face. There is always a danger of disfigurement. This paper reports the experience in treating typicat face burns using moist exposed therapy and the course of the treatment. 5 patients with deep burn in whole face healed in 30 days without skin grafting. The results were very satisfactory. The patients restored their original appearance.

Experience with Moist Burn Therapy in Treating Burn Children

(Abstract)

Zhu Can, et al.

(Kunmillg General Hospital, Chengdu Military Region)

This paper introduces the clinical experience with moist burn therapy in treating burn children. Characteristics of burns in chifdren are described. The problems encountered in conventional therapy and the advantages of moist therapy are discussed and points for attention suggested.

MEBO for Treating Residual Wounds After Exceptionally Severe Burns

(Abstract)

Tao Yexting, at al.

(Dept. of Burn Plastic Surgery, People's Hospital, Xiuliang Uygur Autonomous Region)

Exceptional severe burns treated at the early stage with conventional therapy always leave residual wounds which become recurrent and refractory at the late stage. As the patients are in a state of low immune function and weak physical condition, and the bacteria in the wounds become more resistant to antibiotics, cepticemia often occurs. This is a difficult problem in the treatment of burns. The authors used MEBO for treating 5 cases of exceptionally severe burns with late residual wounds and concluded that MEBO healing of the wounds. MEBO has analgesic and antipruritic effects. These properties of MEBO help to solve the long existing problem. In the course of the treatment. it is very important to give sufficient nutritional supply and supportive treatment. so that better healing of the wounds can be ach ieved.

Nursing Experience in Treating 200 Cases of Burn Using MEBT

(Abstract)

Pan Xiuring, et al.

(Yanzhou Burns, Wounds and Scarce Ulcers, Science and Technology Medical Centre)

This paper reports the experience with moist exposed therapy in treating 200 cases of burn. The largest burn area was 76% Average burn area 11 .28% 64 cases had 3rd degree burn. The largest 3rd degree burn area amounted to 64% Average 3rd degree burn area 7.26% 196 cases healed. Healing rate 98% 4 cases died. Death rate 2% The author summed up the experience with moist exposed therapy including wound management, nursing at the shock stage and fluid therapy. The advantages of MEBO were also discussed.

2 Cases of Decubital Ulcer Treated With MEBO

(Abstract)

Li Fengxiang

(Cangxian County Hospital. Hebei Province )

Patients lying in bed for a long time without proper nursing may have decubital ulcers. The author treated 2 cases of decubital ulcer using M EBO. The resu its were satisfactory.

One case of burn after a. long period of ged stay had a lumbosacral ulcer. 7cm in diameter. The patient was treated with MEBO after debriedement, 3 times a day and was helped to change his posture frequently. The ulcer healed in 50 days. One case of colon cancer post operation had an ulcer 4 cm in diameter. After treated with MEBO the ulcer shrinked to half of its original size in 25 days. The patient died of respiratory and circulatory failure. But before his death, good granulation in the wound was seen and the edge of the wound spread toward the center.

MEBO for Preventing Chilblain

(Abstract)

Han Quanfu, et al.

(Organic Chemical Factory, Jingmen City)

Chilblain is commonly seen in Cold season. Once it happens. it recurs very often.

40 persons including staff and workers of the factory and their family members were divided into two groups. People in the 1st group were treat. ed with MEBO. 4 times a day. for the pUrpose of preventing chilblain formation. People in the 2nd group were not treated. The results revealed that MEBO is very effective for preventing chilblain (P<0.01 ). This is a simple and economical method with promising prospect.

A Specific Remedy for Cold Injury----MEBO

(A Report of 16 Cases)

(Abstract)

Liu Jingwen, at al.

(Hospital for Staff and Workers, Patrochemical Industrial Bureau,Jiamusi City)

The authors treated 1 6 cases of cold injury in the winter of 1989 and 1990, using MEBO. The results were very satisfactory. The authors introduced the general rule of the treatment of cold injury and the methodology of the application of MEBO and made a discussion on typical cases and the mechanism of the healing action of MEBO.

14 Cases of Bone Exposure Healed by MEBO

(Abstract)

Li Fellgckun, ac al.

(Dept. of Burns, No.322 Hospital of PLA)

From May 1989 to February 1991, the authors treated 14 patients with bone exposure caused by cold injury and deep burn. Among them 2 patients had cold injury, 3 patients were burned by electric shock. 2 by molten iron. 1 by hot adobe and 6 by flame. Location of exposed boned 28 bone exposed areas were located in the fingers, 2 in toes. 3 in heels, 1 in anterior tibia and 1 in forehead. One of them after removing necrotic bone cortex had marrow cavity open. Area of exposed bone : the largest 7 x 3.5cm2, the smallest 2 x 1 cm2, average area 3.1 x 1 .5cm2. All the patients healed by treating with MEBO. None of the patients had secondary infection. No skin grafting was needed. The shortest healing period was 12 days and the longest 46 days. Average healing PS. nod 24.7 days. The restoration of the function was found to be very good after followed--up,for 6 months.

Moist exposed therapy gives very good results in treating bone exposure. The therapy is easy and simple and requires no surgical operations. Bone exposure and burn wounds can be healed at the same time, so that the therapeutic course can be shortened. This therapy is suitable for medical units of various levels and is worthy to be popu larized.

6 Cases of Traumatic Skin Necrosis and Muscle Tendon and Bone Exposure Treat6d with MEBO

(Aboact)

Zhao Ckengyu

(Dept. of Orthopedics, Pingzhuang Mining Bureau Hospital)

This paper reports 2 cases of necrosis after skin contusion complicated by muscle tendon exposure. 2 cases of bone exposure and 2 cases of face contusion. treated with MEBO. The wounds in the hands healed spontaneously and the functions of the hands reconstructed. The treatment was not painful and the recovery of the function was satisfactory. The results were better than that of skin grafting and skin flap transference. 2 cases with bone exposed heated without infection. 2 cases with deep second degree col tusion in face healed without scar formation.

MEBO for Treating Wounds Other Than Burn Wounds in Special Parts of the Body

(Abstract)

Yan Ckenghao, et al.

(Debt. of Uroloaical Surgery. Third Peonys's Hospital. Skashi. Hubei Provinc)

MEBO had been used to heal 4 cases of abrasion of perineum and scrotum, complicated by infections and 2 cases of ulcer of glans penis. The results were very satisfactory. MEBO promoted healing of the wounds. The treatment was very simple. No dressing change was needed.

A case of chronic Nasal vesti6untis Treat6d with MEBO

(Abstract)

Wang Yanfen

(Hospital of Electrical Machiners Plant, Harbin)

Chronic nasal vestibulitis is a common bu painful disease. It has a long therapeutic coursf when treated with conventional method. The re suit is often not very satisfactory. The author usec MEBO for treatina a case of chronic nasa vestibu lins. The resu it was miracu lously good. The patient was completefy healed after a consecutive appplication of the ointment for 7 days. No recurrence observed after followed up for 6 months.

Post--peritomy APPlication of MEBO

(Abstract)

Guo Zhentao

(People's Hospital, Lkchu City)

MEBO was applied to the wounds after peritomy to replace the conventionally used vaselin gauze. 20 patients were healed by the first intention without infection. MEBO is effective for preventing dehydration. crust formation, infection and inflammation of the wounds and promotes heating. During the course of dressing change there is no pain and no bleedina.

MEBO for Treating 63 cases of Post Tonsinotomy

(Abstract)

Huan Qingshan

(Urban Central Heswtal. Laiwu. ShandonH Produce)

MEBO is a new drug widely used in clinic, in recent years. It has miraculous efficacy. The author used MEBO for treating 63 cases of post tonsillotomy. The results were very satisfactory. Clinical practice proved that MEBO has analgesic and hemostatic effects and prevents scar formation. Patients treated with MEBO had lower incidence of complications as compared with patients treated with conventional method. (P< 0.01 ).

Oral Atheinistration of MEBO for Treating A Case of Sirers Ulcer of Upper Digestive Tract Post Burn

(Abstract)

Huang Hengliang

(People's Hospital, Laibin County, Guangxi Zhuang Autonomous Region)

The author treated 81 cases of burn using MEBO. The results were very satisfactory. This paper reports a case of oral administration of MEBO. A child of 3, with deep Znd degree burn area amounted to 13%BSA, was found to have hematemesis and repeated hematochezia on the next day post burn. The child was in a state of severe blood loss. Hemoglobin : 309/L. Diagnosis :hemorrhagic shock due to massive hemorrhage caused by stress ulcer of the upper digestive tract. The child was treated with hemostatic agents and Hi antagonists for 3 to 4 days, but hematochezia was not controlled. The condition of the child worsened rapidly. The parents of the child refusedto give the child a surgical operation. For there was no way out. MEBO was administered orally. 2 tubes each time, 5 to 6 times every day. Hematemesis and hematochezia stopped on the next day after oral administration. Test for occult blood became negative in 4 days. The child healed and was discharged on the 16th day post burn.

Facial Defect Repaired by Using Nasolabial Groove Fasica Flap

(Abstract)

Wang Heeing, et al.

(Dept. of Plastic Surgery, No. 159 Hospital of PLA)

Nasolabial groove flap for repairing face defect has proved applicable. But the flap pedicle is short and its application scope is limited.

In the past two years, the authors repaired 3 cases of face defect using nasolabial groove fasica flap. The results were satisfactory. Fasica flap is easy to handle and the operation is simple. Nasolabial groove fasica flap is superior to pedicle vascular flap. There is no need to damage a major vessel. The appearance of the patient after recovery is very good.